What is a corneal epithelial defect?

The cornea is the outermost part of the eye. It serves as both a protective layer and allows light to enter the retina. The cornea has several layers that perform this function. The epithelium is the outermost layer.

The epithelium of the cornea is only a few layers thick, but it protects the eye against dust, debris, and bacteria. This layer can heal itself in most cases if there is a minor injury. However, in some instances, the corneal epithelial defects may be “persistent,” causing serious problems. We will explain what a corneal epithelial deficiency is and what people should know about it.

Overview of persistent corneal epithelial defect

Persistent corneal epithelial deficiency (also known as persistent epithelial defects or PED) is an injury that does not heal within two weeks after treatment. Factors like excessive dryness or trauma cause these defects. They can also be caused by neurotrophic diseases, infections, or even neurotrophic diseases. It is one of the most common injuries that affect the general population.

Corneal epithelial defect symptoms

people with persistent corneal epithelial defect often report feeling a foreign object in their eye, particularly when they blink, as well as pain when moving the eye. Individuals with persistent corneal epithelial defects also experience redness, increased tears, and blurred vision.

Treatment of corneal epithelial defects that persist

Treatment should begin immediately if it is suspected that someone has a persistent epithelial corneal defect. A PED that is not treated properly can increase the risk of infection, scarring, and perforation. It may also cause significant vision loss.

There are several options for treatment depending on the cause. Epithelial defect treatment plans typically include lubrication (to help the eye retain moisture), bandage contact lenses, tarsorrhaphy, topical antibiotics, and punctal plugs.

Due to the severe consequences of persistent corneal epithelial defects, it is important to develop new and effective treatments. But this is only possible through clinical trials. Click the button below to learn more about local clinical trials.

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